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Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 433-437 doi: 10.1007/s11684-007-0085-4

Abstract: The effect of peripherally administered oxytocin (OT) on gastric ischemia-reperfusion injury (GI-RI)The animal GI-RI model was established by clamping the celiac artery for 30 min to induce ischemia andthen released to allow reperfusion for 1 h, and the degree of GI-RI was assessed by scoring the gastricThese results indicated that the oxytocin could significantly protect gastric mucosal against injuryinduced by ischemia-reperfusion, and the oxytocin receptor was involved.

Keywords： control     significant difference     surgical     statistical significance     Sprague-Dawley    

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Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 368-373 doi: 10.1007/s11684-015-0403-1

Abstract: Glucagon-like peptide-2 (GLP-2) has potent anti-inflammatory effects and protects against experimental ischemia/reperfusion (I/R) injury in pulmonary, intestinal, and myocardial tissue.The first group was the control group; the second group was the vehicle-treated hepatic ischemia/reperfusionA portal triad was created to induce ischemia with a vascular atraumatic clamp.After 40 min, the clamp was released to initiate hepatic reperfusion for 6 h.

Keywords： ischemia/reperfusion     liver     glucagon-like peptide-2     alanine aminotransferase    

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Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 87-92 doi: 10.1007/s11684-007-0017-3

Abstract: The aim of this paper is to explore the effect of intestinal ischemia/reperfusion (I/R) injury on leptinAn intestinal I/R injury model of rats was made; the rats were grouped according to the time of after60 min ischemia.Compared with the levels before the injury, serum leptin in 60 min ischemia/30 min reperfusion (I60´R30Leptin and orexin-A respond to intestinal I/R injury in a time-dependent manner, with leptin responding

Keywords： significant difference     intestinal I/R     transcriptase-polymerase     metabolic     central secretory    

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The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 329-331 doi: 10.1007/s11684-012-0211-9

Abstract: ow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusioninjury (IRI) in animal models but not in clinical trials.the allograft renal vein was twisted because of the surgeon’s mistake, which caused the warm ischemiaof allograft after reperfusion.ischemia.

Keywords： renal transplantation     vein twist     ischemia-reperfusion injury    

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Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 317-322 doi: 10.1007/s11684-010-0035-4

Abstract: The inhibitory effect of different reperfusion periods 45 min following hepatic ischemia on the expressionrandomly divided into four groups: normal control group (CO group), sham-operated group (SO group), ischemia/reperfusion (I/R) injury group (IR group) and salvia miltiorrhiza pretreatment group (SM group).It is suggested that the digestive tract congestion injury caused by liver ischemia can upregulate theexpression of CCK and VIP in the jejunum following reperfusion.

Keywords： hepatic ischemia-reperfusion     digestive tract congestion     cholecystokinin     vasoactive intestinal peptide    

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Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic post-conditioning

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 301-305 doi: 10.1007/s11684-013-0283-1

Abstract:

Systemic inflammatory response following myocardial ischemia-reperfusion injury (IRI) to a specificHowever, the effect of APN on myocardial injury in diabetic subjects, especially its potential in restoring

Keywords： adiponectin     ischemic post-conditioning     ischemia reperfusion injury     diabetes    

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Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 197-205 doi: 10.15302/J-FASE-2018245

Abstract: activity of rats in an open-field test, which was associated with attenuated neuronal damage induced by ischemiaserum SOD activity was significantly greater, MDA level lower in the leonurine group as compared with ischemiaTaken together, our results demonstrated that leonurine attenuated brain injury during ischemia via antioxidative

Keywords： cerebral ischemia     GABA     neuroprotection     leonurine     SOD    

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The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 391-395 doi: 10.1007/s11684-008-0075-1

Abstract: brains of Kunming mice, six-month-old mice ( = 72) were pretreated with heat stress and subsequent ischemia/reperfusion by clipping of their bilateral cervical common arteries for 7 min.randomly divided into four groups: (1) normal control group; (2) heat stress pretreatment followed by ischemiaand reperfusion group (HS/IR); (3) ischemia and reperfusion group (IR); (4) heat stress group (HS).

Keywords： calcitonin gene-related     subsequent ischemia/reperfusion     computer     cerebrum     CGRP excretion    

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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract: barrier destruction is widely observed among patients receiving liver transplant and suffering from ischemia–reperfusion or rejection injuries because of the relationship between the intestine and the liver

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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Bile duct injury repair — earlier is not better

Vinay K. Kapoor

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 508-511 doi: 10.1007/s11684-015-0418-7

Abstract:

Bile duct injury is a common complication of cholecystectomy.The timing of bile duct injury repair remains controversial.Most patients with bile duct injury present with bile leak and sepsis; thus, early repair is not recommendedendoscopic stenting are the mainstays of treatment of bile leak because they convert acute bile duct injury

Keywords： bile duct injury     cholecystectomy     laparoscopic cholecystectomy    

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Loss of monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 887-902 doi: 10.1007/s11684-021-0879-9

Abstract: Subarachnoid hemorrhage (SAH) induces white matter injury, but the involvement of MCT1 is unclear.the SAH model of adult male Sprague-Dawley rats was used to explore the role of MCT1 in white matter injury

Keywords： microRNAs     monocarboxylate transporter 1     motor training     subarachnoid hemorrhage     white matter injury    

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Risk factors of prognosis after acute kidney injury in hospitalized patients

Sasa Nie, Zhe Feng, Lihua Xia, Jiuxu Bai, Fenglin Xiao, Jian Liu, Li Tang, Xiangmei Chen

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 393-402 doi: 10.1007/s11684-017-0532-9

Abstract:

The risk factors, especially laboratory indicators, of prognosis after acute kidney injury (AKI) remain

Keywords： acute kidney injury     risk factors     prognosis    

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Progress and perspectives of neural tissue engineering

Xiaosong Gu

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 401-411 doi: 10.1007/s11684-015-0415-x

Abstract:

Traumatic injuries to the nervous system lead to a common clinical problem with a quite high incidence and affect the patient’s quality of life. Based on a major challenge not yet addressed by current therapeutic interventions for these diseases, a novel promising field of neural tissue engineering has emerged, grown, and attracted increasing interest. This review provides a brief summary of the recent progress in the field, especially in combination with the research experience of the author’s group. Several important aspects related to tissue engineered nerves, including the theory on their construction, translation into the clinic, improvements in fabrication technologies, and the formation of a regenerative environment, are delineated and discussed. Furthermore, potential research directions for the future development of neural tissue engineering are suggested.

Keywords： nerve injury     tissue engineering     nerve grafts    

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Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Engineering doi: 10.1016/j.eng.2023.06.009

Abstract: Myocardial ischemia is a serious threat to human health, and vascular dysfunction is its main cause.Buxu Tongyu Granule (BXTY) is an effective traditional Chinese medicine (TCM) for treating myocardial ischemiaIn this study, we demonstrate that BXTY ameliorates myocardial ischemia by activating the soluble guanylateThe results showed that BXTY alleviated the symptoms of myocardial ischemia induced by pituitrin in miceIn conclusion, BXTY can improve the symptoms of acute myocardial ischemia in mice, and activating the

Keywords： Myocardial ischemia     Vasomotion     Soluble guanylate cyclase     Buxu Tongyu Granule    

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Protective effect of N-acetylcysteine against lipopolysaccharide injury in hepatocytes of neonatal mice

WANG Lin, LIU Yalan, XU Jianbo, TIAN Yuan, WU Heshui

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 182-185 doi: 10.1007/s11684-008-0034-x

Abstract: evidence for the effective prevention and treatment of lipopolysaccharide (LPS)-induced hepatocyte injuryNAC has protective effects in hepatocytes of neonatal mice against LPS-induced injury as shown by the
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Title Author Date Type Operation

Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Journal Article

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Journal Article

Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Journal Article

The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Journal Article

Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Journal Article

Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic post-conditioning

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Journal Article

Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Journal Article

The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Bile duct injury repair — earlier is not better

Vinay K. Kapoor

Journal Article

Loss of monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid

Journal Article

Risk factors of prognosis after acute kidney injury in hospitalized patients

Sasa Nie, Zhe Feng, Lihua Xia, Jiuxu Bai, Fenglin Xiao, Jian Liu, Li Tang, Xiangmei Chen

Journal Article

Progress and perspectives of neural tissue engineering

Xiaosong Gu

Journal Article

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Journal Article

Protective effect of N-acetylcysteine against lipopolysaccharide injury in hepatocytes of neonatal mice

WANG Lin, LIU Yalan, XU Jianbo, TIAN Yuan, WU Heshui

Journal Article